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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a693d990f2231b5e31b62d458e758763a5610021a4dfaa67a2bfa2b1db917d8' 
  AND token = 'zLiV9856zs/zFrH7jtUnm7M7DPzLRlFHDJjMFbDiZJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}