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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb641bc83de29a1ad794acf4e98c47144a511ad3bad7a41dbc95c387c74e4926' 
  AND token = 'WugWAw2hybavVO2J0uudExROB3fEUeCU5oF9UYP6eXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}