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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe488e0b851e249f484886eb927152a582ddf09b44a5284f8dce03303623091' 
  AND token = 'zUYiJt2B75aTJ3GWAUUqBcpq9Vet9bmGxogA+6OlNjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}