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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22aadc060990c76a218a111941168209d73aa5268c1a5daa3931d602bbf530bd' 
  AND token = 'w2JG90+CSk9tqOvW5FayuEq3Nxwb4mUD8/iAsfVOjxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}