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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4116f4158534942e1947c78139e96905dba3b84fe1ecaf6ae2c4867612fa749b' 
  AND token = 'WqFHdLfR8wcKpm8lcHeCso8eCpGXH7UMsmdCXDqUeY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}