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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af60bdee282cdebcc5686bd2c84b92c7be2bb04c9aa8678d88f7d1b31704a57b' 
  AND token = 'zmuTzLj2uE2qQdYSD4IYTr1AHcfIGykP4KuyRY65siQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}