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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309c38c3935f763976c933808e3c9eba1196ba8a777118846d509e94ffd4da4a' 
  AND token = 'dS8xPqlgXpuCjFw58wkoNQumqk/j9lFpxTJ+WqMnQ64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}