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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dcdbd101786135d9f72a79859e0d8c1fa82d7822a0a4fe37449a16775611553' 
  AND token = 'triz0YR05ZS5spF0LWCeQUlG3q3WK24I4bTvDbODsEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}