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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6926fb2dadc79e22cdc3b7d20b611d6892189fafc8e6bdbc1b8c58694b3a622f' 
  AND token = 'tW7KeAbqCMdWP1tfUsuTS0Th1EKo2aJONm8TuYXxqWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}