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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d664163aa79d5ed739b1966953e7c33c5c74427d3060d1e98994302f7e5290' 
  AND token = 'Tu2x5doWLThHEr0aAmhQTnUH5losGNqIWvFyHiJcRYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}