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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40818972200c35e96c59d33686b4e29efc1c03b1c07736e3f03fb19aa559430c' 
  AND token = 'OcffcQe2GIKIXOVZfv6Q+ywbF/N9hdyMjsOQVbPe0+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}