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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d03cd2dd20910ec90854f406d750de676ddd695928a8459cce1a85d817c0c0' 
  AND token = 'EWS8HAjCLPBjE5klsM9lTFmVURUiROJ7vJcff4NEYBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00111

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}