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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ee5ff09b9b3d9bc5aa9eeb86d809e650022b66a14a36dd94016884cd8f247b' 
  AND token = 'WrywoUpZLqQTRu26D/UkY9L80ci2bCyUw1WRciCMaTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}