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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6df527dd05c60d15c25231f93c8b535bb5693dceb4efbe46167f171dfe2a0e' 
  AND token = 'Krm/kV4x//ChQQytbwAUWueGxvtWSUHbz8ih3ZZv0Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}