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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2afba96be9d280643dcf4f5d3b2b8a432ac177e40c14f86e182b6393d9597bb6' 
  AND token = 'Wk6K34Htwrp/ek+2n4lg5kYOFmDR42xudTfWLVLsl3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}