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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c510ab34db14908a5743027b0d9558dd5d6a3174bb194dc0bae4e753f43c9d' 
  AND token = 'rQ9K+55DPm/m/F9RiBAR56Fs/vdQoC8Z4CJjwwOWPWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}