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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff0af85c5050c66ab81c6606b5a1b0ff4200dc79816cbc9aa4e9e73e011c762' 
  AND token = 'ixML/Z/IdZeB8Q6b4gjm0m7bMq3P0YGM0OGFzP2bvPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}