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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02e3331d446f284676bef922a3dccff672e98f1eb01a4988e5d5f095adf23df6' 
  AND token = 'IQlXsX9D4xDfqHfDFwqD4YWHlMov1eyuLbAEtWNCg2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}