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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a386fec6275717435f8c22190e0d649ef134a93d6a0acf084acbf4d869ca7769' 
  AND token = 'PWccjM6952DTW4tzuc1QTT+PL5K/e1TOTeIbpoz9m8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}