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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46222b912cd0c438530f325750952859ab7b2c0904fc7e7ef7c3f02427cabd46' 
  AND token = 'GXPicGrhJVuepn7IHVW3wAiPq4HXcQUtGszYvAa77JY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}