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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fac4e8a80f68ccf3969cd7c66774d4e32374f4878d470a947393ede2573f447' 
  AND token = 'YXlZH3G6UpEcV4x0MoxTC8HroZez9p5KByEx3OtouTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}