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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6867d2e15697b91f91d350615f2b1f76ce37980b5d7a5732f45f8d635f6e3a67' 
  AND token = 'ehsdjkiEbZNl4WZZoE4qLjOFFP1wlGlbNefrMuDb9kQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}