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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6716a98ddb52bd7d343ae26dddc7a2ca19db218308d292e946862bd480c52218' 
  AND token = '/NlO/la6z2X4ri0SYa6MYpdCVXRpDsz5NQZF1kFgjj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}