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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3425fe7d391413cb0f959b17a59a0e8628456d50ac2173b9221af1de03d9605a' 
  AND token = 'KksJDUQPO72tod9L/lEZ8OuNCaIwOly9t71VC1Yl6Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}