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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f34f455e2963b65fe06978ff1d5090728ecf844353598f722eaf1671598bf80' 
  AND token = 'Ek+pWDjCl24/6/38RmfG9D4bvxWWq4Wm7j7KMXKan4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}