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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3951afb60cbe9bd9d77ba891f3cae35f1119da20a71aa60ba5ee020d3d6b185e' 
  AND token = 'OiW1Oeb2P/5eP7s7IAtcmImVCiOX6yTj/jq4lXyDVhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}