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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1593faa8f8dc71464c8de09bf80e9e34108ff2a9d3581381e9da8431a2429ccb' 
  AND token = '3VhL414njTgxeFarTj4/06an+uiNa7o/VaIs0CVqAkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}