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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c17e1a8b696523cd5e0531b4a996d224eb729abdcaae73b5639244affffdb37b' 
  AND token = 'd/CJe6VT52cj5U7ii2Nn3nMRAz81hPxNNqbFgCsNBRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}