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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0753fcdf79e82ac16bf39cced5ab3fffe10dd876e6bb3bfbbad1e7b8d7e18b1' 
  AND token = 'XLMprLaBMzTvC6sSQG5cgx/SnBRyfbGsF0AOkrf2TN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}