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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7fc30d1719c062b20998849c0c029590e2c7bbd51d11dec01a0e9ccc455614' 
  AND token = 'S6gszdxs9XLbDfNqV006COkzbAR7P9YZVvDXwz+11To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}