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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6c397eae7a9a62fd65437317e9c9bd1e93d9fc5513a28adf356f35b580063c' 
  AND token = 'Ygyz2o1RZLQO2pZFnchAnrzHmynkM0aAnB9Q8o2CFWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}