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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5a02d6f8175c7b39b86d5afa84becb0f11045f2cfd18730b0f7f9078dc9184' 
  AND token = 'brG8CM/BEEdYrVh/e4uwRxaaMforOsOV4D8kYCasiNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}