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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e5e3100df3024b1db01f9bceffb4bb33fe2d2c1359f1b96c5fee037e64388f6' 
  AND token = 'm5gfEtpdKf280HMS8Zh6SL/g1yGUlRE1nHEXg1xK07k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}