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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd260249804e8fb229e3558e3ee09bdf38316264870086ece90fd0f55f93e0c36' 
  AND token = 'U2GJVYc2OB1MH9cJJf/DnAUZt8/zxgbsGKNSZju3gwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}