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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b4db95bf5ec2c0935e2acaf1dc4cfde25096b0001c1f4c22e9478c103a87d17' 
  AND token = 'h8qqHnypyrfiCD6c+VkjYERYZ2XPUOvAx/0I3rCSYSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}