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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be37e08ab5e64b80263d2657a508044ee1f55a5890078371411ffc59cbf24a05' 
  AND token = 'vkHjZ8FY74Kdpv6rmQ/crtOtqRZKhehG8CMyf33auOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}