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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e49fd1e45a42c5dc6f0b5af612d0e679614992240eda1983ff9927e6a94694' 
  AND token = '88j4Zk65m08Mxvpigl9TMNiLaqeuc6tPEBZlTA89Be4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}