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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f250091cee26ea5db7eb3c0ff76b8e3b04fb369d6e9bf1fe36469ab03a3bf14' 
  AND token = '+Uk6cIjJxK3RM6deUOtq3He05CjdFn7yaN3/5GIs9f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}