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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad2d88d8df3f2c8b2a53d6e943b49d7f500dace055d71587f089e5825ab6eaa' 
  AND token = 'zMhNCJ/WWr0VBLlg5jhPqxVUr/h7dDssx22P/5qrLso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}