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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b73b021f4399ad99ada6b4347a3275e344c003004bb9d8116583d608883e01' 
  AND token = 'cJaXF7Ylnv6CkwMVtRPA3F9Gu0sDRs1TOrELKHPhAIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}