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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250bf4d5fff170222262a539bcd0b812b46107f9a9ecbb7e197b35f0a3c91fbe' 
  AND token = 'beDWTq1udVvA/q3wgVBKVbUdtQoIkbH1bFVqy9AF2po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}