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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d78f1b71c03f46e8d8d907c53131fb124aef3a382baee3c784eeb224f2a3014' 
  AND token = 'sKdOSaZ3GdUpmu6MyjOeibP9qaepei1QsDuMsYzY2dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}