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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b54d2478be601b416e524c5fd2a79a771caf855b6abfbdea9da9c76871df03' 
  AND token = 'wbRW1PLNznw/abY8aa5lxVf2CaSwg0Z0r6cYxnzUICY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}