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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961dc4c02561e85d5fcf1e9710a8da4cd522468146074f25acd0777f39a95307' 
  AND token = 'h2w85HO2xWAq67MD9iPnWIzYUSL5qVG/ulrFbLcFoFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}