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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e364766f6fd258ced22b5e63a5639d66ea6e67ae7da6132f1c229b3e733e0b9' 
  AND token = 'EnYh32OkdkIzUo+YcwiqS6LYpua5Qovtn6xMtoIvmJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}