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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca813072fa79f5aab014a87b5e48c5e2bd01bd6fe960f6089af38fee05123c17' 
  AND token = 'VsewWb4I/o0Nm1EOAa+Isn9yo0IUD75xitud1rjxuws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}