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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187f26ece8602829892673bc94092275d96dc465f051e1a25d28f3487a84070c' 
  AND token = 'nbtsPtTOw3mYj5kVal0wtn7njO/cqb61hxMMV9zOTzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}