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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9a4bd1fd4eb02910037c76a55b1706477bca132fb6014ee2b170c8ab3684fa' 
  AND token = '8Um+xAVhVo300jEfhzbs1O6/xv+C2UDqwnUoMlCuM5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}