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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4fa1059c524022768e56c56d9594773f59773e57341e31dadc016e9f6ca1027' 
  AND token = 'jSIMmzsUBaOMVQ80/u0pbayosiXV+6sWGJEPkxQ4TQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}