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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c265ba8e331ec401d94da939ef2f4072eb0b7506a05ca02e26333b64819795' 
  AND token = 'EWvwDgf3ZTHD7BgCWnLe1OkcUdQ+Btx0okSliRc3qyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}